Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184925 | 0.78 | — | — | |
| SCHEMBL1367536 | 0.78 | — | — | |
| Tert-Butyl Formate SCHEMBL28110092 | 0.76 | TDP1 (0.56) | TDP1 | |
| Hydrochloric Acid SCHEMBL28852943 | 0.75 | — | — | |
| Tert-Butyl Formate SCHEMBL27637916 | 0.74 | TDP1 (0.54) | TDP1HPGDSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28094436 | 0.74 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28792406 | 0.74 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28313648 | 0.74 | TDP1 (0.48) | TDP1HPGDGAAEPHX2KMT2A | |
| Tert-Butyl Formate SCHEMBL27361307 | 0.72 | TDP1 (0.56) | TDP1KMT2A | |
| Tert-Butyl Formate SCHEMBL28276350 | 0.72 | TDP1 (0.56) | TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934246-B | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110198940-A | N- [ 4-fluoro-5- [ [ (2S,4S) -2-methyl-4- [ (5-methyl-1, 2, 4-oxadiazol-3-yl) methoxy ] -1-piperidinyl ] methyl ] thiazol-2-yl ] acetamide as OGA inhibitors | 伊莱利利公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-105934246-A | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2016-09-07 | — | — | CN | disclosed |