Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28290799 | 0.89 | TDP1 (0.45) | TDP1GAAHPGDLMNA | |
| Tert-Butyl Formate SCHEMBL27721997 | 0.83 | TDP1 (0.50) | TDP1GAAHPGDLMNAALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28110092 | 0.80 | TDP1 (0.56) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27639043 | 0.80 | TDP1 (0.42) | TDP1GAAHPGDLMNAALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27637916 | 0.79 | TDP1 (0.54) | TDP1HPGDNPC1SMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28094436 | 0.78 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28792406 | 0.78 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28811787 | 0.77 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27634274 | 0.76 | TDP1 (0.56) | TDP1KMT2A | |
| Tert-Butyl Formate SCHEMBL27639671 | 0.76 | TDP1 (0.56) | TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |