Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 18/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157654 | 0.90 | NPC1 (0.58) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL15706755 | 0.90 | HSD11B1 (0.54) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL15706769 | 0.90 | NPC1 (0.58) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL14157597 | 0.90 | HSD11B1 (0.54) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL14157555 | 0.90 | HSD11B1 (0.48) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL15706806 | 0.90 | HSD11B1 (0.48) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL15706726 | 0.89 | HSD11B1 (0.54) | HSD11B1HSD11B2 | |
| SCHEMBL14157716 | 0.89 | HSD11B1 (0.54) | HSD11B1HSD11B2 | |
| SCHEMBL15706730 | 0.88 | HSD11B1 (0.60) | KDM4ENPC1ALDH1A1LMNARAB9A | |
| SCHEMBL14157623 | 0.88 | HSD11B1 (0.60) | KDM4ENPC1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649066-B | 5-carbamyl-diamantane (obsolete)-2-yl amide derivatives, its pharmaceutically acceptable salt and preparation method thereof | 爱思开生物制药株式会社 | 2016-08-17 | — | — | CN | claimed |
| CN-103649066-B | 5-carbamyl-diamantane (obsolete)-2-yl amide derivatives, its pharmaceutically acceptable salt and preparation method thereof | 爱思开生物制药株式会社 | 2016-08-17 | — | — | CN | disclosed |