Sugi Predict

Sugi Predict / Compounds / SCHEMBL28094976

SCHEMBL28094976

SCHEMBL28094976

Cc1ccccc1-c1ccc(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)s1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 19/20 0.48
▸ HSD11B2 P80365 2/20 0.48
▸ HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14157651 0.90 HSD11B1 (0.51) HSD11B1HSD11B2
SCHEMBL15706805 0.90 HSD11B1 (0.51) HSD11B1HSD11B2
SCHEMBL15706771 0.89 HSD11B1 (0.56) HSD11B1
SCHEMBL14157728 0.89 HSD11B1 (0.56) HSD11B1
SCHEMBL15706777 0.85 HSD11B1 (0.53) HSD11B1HSD11B2
SCHEMBL14157556 0.85 HSD11B1 (0.53) HSD11B1HSD11B2
SCHEMBL15706765 0.83 HSD11B1 (0.50) HSD11B1HSD11B2
SCHEMBL14157621 0.83 HSD11B1 (0.50) HSD11B1HSD11B2
SCHEMBL14157563 0.82 HSD11B1 (0.55) HSD11B1HSD11B2
SCHEMBL14157730 0.82 HSD11B1 (0.53) HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103649066-B 5-carbamyl-diamantane (obsolete)-2-yl amide derivatives, its pharmaceutically acceptable salt and preparation method thereof 爱思开生物制药株式会社 2016-08-17 — — CN claimed
CN-103649066-B 5-carbamyl-diamantane (obsolete)-2-yl amide derivatives, its pharmaceutically acceptable salt and preparation method thereof 爱思开生物制药株式会社 2016-08-17 — — CN disclosed
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