Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531059 | 1.00 | MAPT (1.00) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL28095200 | 1.00 | MAPT (1.00) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL14148892 | 1.00 | MAPT (1.00) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL32679236 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL32679235 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL1917252 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL29357137 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL31286546 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL4812487 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 | |
| SCHEMBL1917292 | 0.90 | MAPT (0.84) | MAPTLMNAHPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315623-B | Method for synthesizing xanthoxylin WGX-50 and its derivative in one pot | 上海彤颜实业有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114917365-A | WGX50 cyclodextrin inclusion compound, preparation method, solubility and cyclodextrin inclusion rate determination method | 上海彤颜实业有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114315623-A | Method for synthesizing sanshoamides WGX-50 and derivatives thereof in one pot | 上海彤颜实业有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-103130674-B | Prevention and the potential drug gx50 for the treatment of alzheimer's disease, the chemical synthesis process of gx51, gx52, gx180 | 无锡枫华生物科技有限公司 | 2016-09-07 | — | — | CN | disclosed |