SCHEMBL28095249

SCHEMBL28095249

FC(Cc1ccccc1)OC(F)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
SIGMAR1 Q99720 5/20 0.44
TAAR1 Q96RJ0 4/20 0.44
SLC6A2 P23975 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
CYP1A2 P05177 1/20 0.43
SLC18A2 Q05940 1/20 0.41
ANPEP P15144 1/20 0.41
CYP2D6 P10635 1/20 0.41
SRR Q9GZT4 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1287175 0.77 EPHX1 (0.50) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL4135262 0.76 CYP1A2 (0.41) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL184702 0.76 EPHX1 (0.55) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL30657566 0.76 EPHX1 (0.55) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL7889486 0.74 EPHX1 (0.52) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL4135267 0.73 CYP1A2 (0.42) EPHX1CYP1A2ANPEPSRR
SCHEMBL4126547 0.73 CYP1A2 (0.42) CYP1A2ANPEPSRR
SCHEMBL5609928 0.72 EPHX1 (0.50) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL5027439 0.72 EPHX1 (0.64) EPHX1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL1033148 0.72 SIGMAR1 (0.58) EPHX1SIGMAR1TAAR1SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106025344-B Flame-retardant electrolyte for lithium ion battery 东风商用车有限公司 2019-02-01 CN disclosed
CN-106025344-A Flame-retardant electrolyte for lithium ion battery 东风商用车有限公司 2016-10-12 CN disclosed