Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | GAA | P10253 | 9/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396662 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL38662825 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL30779659 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL4344048 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL2730951 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL12597633 | 0.80 | ALDH1A1 (0.61) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL8692433 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL1429238 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL29956404 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL3036074 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003995-B | Pyranone also [3,4-b] indole derivatives and synthetic method thereof | 上海交通大学 | 2016-10-26 | — | — | CN | disclosed |