Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.58 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522787 | 0.89 | EGLN1 (0.65) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL28095852 | 0.85 | EGLN1 (0.52) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL27773936 | 0.81 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522789 | 0.77 | EGLN1 (0.52) | EGLN1BBOX1FTOKDM4EMEN1 | |
| SCHEMBL2015310 | 0.74 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522744 | 0.73 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL29390250 | 0.73 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523061 | 0.72 | EGLN1 (0.60) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522788 | 0.72 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL6060435 | 0.72 | ALDH1A1 (0.47) | EGLN1BBOX1FTOTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242817-B | HIF1 alpha modulators purposes in treatment cancer | 菲布罗根公司 | 2016-08-31 | — | — | CN | disclosed |