SCHEMBL28096016

SCHEMBL28096016

N#Cc1cccc(Oc2cccc(N)c2)c1C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 2/20 0.45
POLB P06746 2/20 0.42
MAPT P10636 2/20 0.42
HSP90AA1 P07900 1/20 0.42
ALDH1A1 P00352 6/20 0.42
GAA P10253 3/20 0.41
CYP3A4 P08684 2/20 0.41
USP2 O75604 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
AR P10275 3/20 0.38
CYP19A1 P11511 1/20 0.38
TP53 P04637 1/20 0.38
ATM Q13315 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617521 1.00 MAOB (0.47) MAOBSMN1; SMN2KDM4EPOLBMAPT
SCHEMBL31183019 1.00 MAOB (0.47) MAOBSMN1; SMN2KDM4EPOLBMAPT
SCHEMBL201559 0.90 MAOB (0.53) MAOBSMN1; SMN2POLBMAPTHSP90AA1
SCHEMBL29492474 0.90 MAOB (0.53) MAOBSMN1; SMN2POLBMAPTHSP90AA1
SCHEMBL3131523 0.89 MAOB (0.52) MAOBSMN1; SMN2POLBMAPTHSP90AA1
SCHEMBL17085525 0.89 MAOB (0.52) MAOBSMN1; SMN2POLBMAPTHSP90AA1
SCHEMBL21352429 0.89 SMN1; SMN2 (0.50) MAOBSMN1; SMN2KDM4EPOLBMAPT
SCHEMBL6511189 0.87 MAOB (0.55) MAOBSMN1; SMN2KDM4EPOLBMAPT
SCHEMBL13712609 0.84 MAOB (0.47) MAOBSMN1; SMN2KDM4EPOLBMAPT
SCHEMBL1362882 0.84 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EPOLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775716-B Halogen-free copper-clad plate substrate material containing flame-retardant modified benzoxazine resin and preparation method thereof 明光瑞智电子科技有限公司 2025-05-30 CN claimed
CN-119775716-A Halogen-free copper-clad plate substrate material containing flame-retardant modified benzoxazine resin and preparation method thereof 明光瑞智电子科技有限公司 2025-04-08 CN claimed
CN-119503774-A High-capacity resin-based hard carbon negative electrode material containing phosphorus and nitrogen double doping and preparation method thereof 中国民用航空飞行学院 2025-02-25 CN claimed
CN-118994765-A Insulation and pressure-resistant material for cable 安徽朗达电线电缆有限公司 2024-11-22 CN claimed
CN-117700786-A High-glass transition temperature high-dielectric polyaryl ether nitrile composite material and preparation method and application thereof 西南民族大学 2024-03-15 CN claimed
CN-116854912-A Simple and environment-friendly method for synthesizing high-carbon-residue low-expansion phthalonitrile resin 四川金象赛瑞化工股份有限公司 2023-10-10 CN claimed
CN-115386369-B Preparation method of fluorescent probe for nickel ion detection 电子科技大学 2023-08-11 CN claimed
CN-116003845-A GO-g-BT/PVDF composite membrane and preparation method and application thereof 成都中浦石墨烯应用技术有限公司 2023-04-25 CN claimed
CN-112645983-B Additive type crosslinkable flame retardant and preparation method thereof 中国民用航空飞行学院 2023-02-24 CN claimed
CN-115386369-A Preparation method of fluorescent probe for nickel ion detection 电子科技大学 2022-11-25 CN claimed
CN-115340651-A Norbornene-nitrile-siloxane type benzoxazine resin and preparation method thereof 济南大学 2022-11-15 CN claimed
CN-113429626-B Cross-linkable flame retardant containing bis-DOPO bis-phthalonitrile, and preparation method and application thereof 中国民用航空飞行学院 2022-05-27 CN claimed
CN-114133760-A High-temperature corrosion-resistant composite material with excellent mechanical properties and preparation method thereof 宁国中奕橡塑有限公司 2022-03-04 CN claimed
CN-113429626-A Cross-linkable flame retardant containing bis-DOPO bis-phthalonitrile, and preparation method and application thereof 中国民用航空飞行学院 2021-09-24 CN claimed
CN-112645983-A Additive type crosslinkable flame retardant and preparation method thereof 中国民用航空飞行学院 2021-04-13 CN claimed
CN-112250712-A DOPO-containing bisphthalonitrile flame retardant and preparation method and application method thereof 中国民用航空飞行学院 2021-01-22 CN claimed
CN-107400359-B Phthalonitrile, benzoxazine and tetra-amino phthalocyanine lead-based anti-radiation composite material and preparation method thereof 哈尔滨工程大学 2020-06-16 CN claimed
CN-106046361-A Cross-linking type polyarylene ether nitrile and preparation method thereof 电子科技大学 2016-10-26 CN claimed
CN-116003845-B GO-g-BT/PVDF composite membrane and preparation method and application thereof 成都中浦石墨烯应用技术有限公司 2025-07-22 CN disclosed
CN-106046361-A Cross-linking type polyarylene ether nitrile and preparation method thereof 电子科技大学 2016-10-26 CN disclosed