SCHEMBL1362882

SCHEMBL1362882

N#Cc1cccc(Oc2ccc(N)cc2)c1C#N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
KDM4E B2RXH2 2/20 0.53
GAA P10253 2/20 0.50
POLB P06746 1/20 0.50
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
ALDH1A1 P00352 6/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MITF O75030 1/20 0.43
GFER P55789 1/20 0.43
NLRP1 Q9C000 1/20 0.43
NOD2 Q9HC29 1/20 0.43
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAOA P21397 1/20 0.41
TLR8 Q9NR97 2/20 0.39
AR P10275 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012743 1.00 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL31456559 1.00 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL7192577 0.90 NCOA1 (0.49) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL8462720 0.88 ALDH1A1 (0.52) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL30777312 0.88 NCOA1 (0.47) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL17085522 0.88 NCOA1 (0.47) SMN1; SMN2KDM4EGAAPOLBNCOA1
SCHEMBL9745478 0.85 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EGAAPOLBALDH1A1
SCHEMBL9745662 0.85 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EGAAPOLBALDH1A1
SCHEMBL20511067 0.85 KDM4E (0.54) SMN1; SMN2KDM4EGAAPOLBALDH1A1
SCHEMBL9359794 0.85 KDM4E (0.54) SMN1; SMN2KDM4EGAAPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081405-A Resin material for halogen-free high Tg low dielectric loss copper-clad plate and preparation process 重庆德凯实业股份有限公司 2024-12-06 CN claimed
CN-118638048-A Phthalonitrile monomer containing pyridine structure and flexible chain segment and resin thereof 天津大学 2024-09-13 CN claimed
CN-118620266-A High-temperature-resistant wave-transparent phthalonitrile modified cyanate resin composite material, preparation method and application 电子科技大学 2024-09-10 CN claimed
CN-118325285-A Glass fiber reinforced aromatic nitrile resin composite material and preparation method thereof 电子科技大学 2024-07-12 CN claimed
CN-118307956-A Polyacrylonitrile composite material, preparation method thereof and automobile part 中国第一汽车股份有限公司 2024-07-09 CN claimed
CN-118239873-A Di-phthalonitrile monomer, resin and preparation method thereof 大连理工大学 2024-06-25 CN claimed
CN-118165512-A Preparation method of low-dielectric mica@polyphenyl ether modified nitrile group BT resin composite material 四川金象赛瑞化工股份有限公司 2024-06-11 CN claimed
CN-114685858-B Magnetic carbon nano tube composite material, wave-absorbing coating, wave-absorbing honeycomb, preparation method and application 深圳光启高端装备技术研发有限公司 2024-03-08 CN claimed
CN-117430917-A Phthalonitrile resin composition for packaging power device 无锡创达新材料股份有限公司 2024-01-23 CN claimed
CN-117327275-A High heat-resistant resin and preparation method thereof 中国人民解放军国防科技大学 2024-01-02 CN claimed
CN-115960436-A Hot-melt bisphenol type cyano-containing benzoxazine resin, prepreg cloth, composite material and preparation method thereof 北京航空航天大学 2023-04-14 CN claimed
CN-115896984-A Oil agent for high-performance high-temperature-resistant polyester industrial yarn and preparation method thereof 上海丰泽源科技有限公司 2023-04-04 CN claimed
CN-115504907-A Phthalonitrile monomer containing binaphthyl structure and resin thereof 河北工业大学 2022-12-23 CN claimed
CN-114685858-A Magnetic carbon nanotube composite material, wave-absorbing coating, wave-absorbing honeycomb, preparation method and application 深圳光启高端装备技术研发有限公司 2022-07-01 CN claimed
CN-112940433-A Environment-friendly degradable plastic material and preparation method thereof 东燊新材料科技(深圳)有限公司 2021-06-11 CN claimed
CN-107400359-B Phthalonitrile, benzoxazine and tetra-amino phthalocyanine lead-based anti-radiation composite material and preparation method thereof 哈尔滨工程大学 2020-06-16 CN claimed
CN-108442122-B Sizing agent for preparing quartz fiber/nitrile resin composite material 湖南师范大学 2019-08-27 CN claimed
CN-106967001-B A kind of ternary benzoxazine-phthalonitrile intermediate, preparation method and its polymer 杭州中一科技有限公司 2019-06-18 CN claimed
CN-108442122-A Sizing agent for preparing quartz fiber/nitrile resin composite material 湖南师范大学 2018-08-24 CN claimed
CN-103289089-B Method for preparing triple phenol type poly-phthalonitrile resin with alkyl center UNIV HEBEI TECHNOLOGY 2015-02-18 CN claimed