Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543178 | 0.80 | MAPT (0.53) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL17899525 | 0.78 | MEN1 (0.66) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11831810 | 0.78 | DYRK2 (0.51) | DYRK2MAPTLMNANPSR1XDH | |
| SCHEMBL29929418 | 0.77 | DYRK2 (1.00) | DYRK2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11845990 | 0.77 | DYRK2 (0.69) | DYRK2MAPTLMNAMEN1KMT2A | |
| SCHEMBL11845989 | 0.77 | DYRK2 (0.69) | DYRK2MAPTLMNAMEN1KMT2A | |
| SCHEMBL7122621 | 0.77 | DYRK2 (1.00) | DYRK2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL13036873 | 0.77 | DYRK2 (1.00) | DYRK2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11821606 | 0.77 | DYRK2 (0.69) | DYRK2MAPTLMNAMEN1KMT2A | |
| SCHEMBL7122623 | 0.77 | DYRK2 (1.00) | DYRK2MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083557-A | α, β unsaturation cyclohexanone derivative and application thereof | 武汉理工大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106008324-A | Alpha,beta-unsaturated compounds and application thereof | 武汉理工大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106083557-A | α, β unsaturation cyclohexanone derivative and application thereof | 武汉理工大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-106008324-A | Alpha,beta-unsaturated compounds and application thereof | 武汉理工大学 | 2016-10-12 | — | — | CN | disclosed |