Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MIF | P14174 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096067 | 0.80 | DYRK2 (0.63) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17899525 | 0.78 | MEN1 (0.66) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL14571667 | 0.78 | DYRK1A (0.51) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL5584115 | 0.78 | DYRK1A (0.51) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL3581744 | 0.77 | MIF (0.64) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL17691388 | 0.77 | MIF (0.64) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL3581740 | 0.77 | MIF (0.64) | MAPTMEN1KMT2AMIFALDH1A1 | |
| SCHEMBL17691411 | 0.77 | IKBKB (0.64) | MEN1KMT2AMIFALDH1A1NPSR1 | |
| SCHEMBL3583600 | 0.77 | MIF (0.53) | MAPTMEN1KMT2AMIFNPC1 | |
| SCHEMBL3583598 | 0.77 | MIF (0.53) | MAPTMEN1KMT2AMIFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001824-A1 | COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS | BAYLOR COLLEGE OF MEDICINE (US) | 1993-02-04 | — | — | WO | claimed |
| WO-1993001824-A1 | COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS | BAYLOR COLLEGE OF MEDICINE (US) | 1993-02-04 | — | — | WO | disclosed |