SCHEMBL28096375

SCHEMBL28096375

O=C(O)c1ccc(C(=O)O)c(OC(=O)c2ccccc2)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.73
ESR2 Q92731 2/20 0.73
KDM4E B2RXH2 5/20 0.54
MAPT P10636 4/20 0.51
KMT2A Q03164 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
GAA P10253 2/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
MEN1 O00255 3/20 0.46
JAK2 O60674 1/20 0.45
USP2 O75604 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28489218 0.95 ESR1 (0.65) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL10784196 0.93 ESR1 (0.63) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL10782540 0.92 ESR1 (0.62) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL28087705 0.90 ESR1 (0.59) ESR1ESR2KDM4EMAPTHSD17B10
SCHEMBL11285516 0.88 ESR1 (0.58) ESR1ESR2KDM4EMAPTHSD17B10
SCHEMBL24808008 0.86 TSHR (0.62) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL5179548 0.85 ESR1 (1.00) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL9785919 0.85 ESR1 (0.71) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL7085249 0.85 MAPT (0.62) ESR1ESR2KDM4EMAPTKMT2A
SCHEMBL6318748 0.83 MAPT (0.61) ESR1ESR2KDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284823-B Crystalline porous material and preparation method and application thereof 西安工业大学 2024-05-14 CN claimed
CN-116284823-A Crystalline porous material and preparation method and application thereof 西安工业大学 2023-06-23 CN claimed
CN-116284823-B Crystalline porous material and preparation method and application thereof 西安工业大学 2024-05-14 CN disclosed
CN-116284823-B Crystalline porous material and preparation method and application thereof 西安工业大学 2024-05-14 CN disclosed
CN-116284823-A Crystalline porous material and preparation method and application thereof 西安工业大学 2023-06-23 CN disclosed
CN-116284823-A Crystalline porous material and preparation method and application thereof 西安工业大学 2023-06-23 CN disclosed
CN-106046032-B A kind of metal-organic framework material, synthetic method and its catalytic applications that is constructed based on 5-membered aromatic carboxylic acid 三峡大学 2017-03-15 CN disclosed
CN-106046032-B A kind of metal-organic framework material, synthetic method and its catalytic applications that is constructed based on 5-membered aromatic carboxylic acid 三峡大学 2017-03-15 CN disclosed
CN-106076419-A A kind of load type metal organic frame composite, preparation method and applications 三峡大学 2016-11-09 CN disclosed
CN-106046032-A MOF (metal-organic framework) material constructed on basis of pentabasic aromatic carboxylic acid as well as synthesis method and catalytic application of MOF material 三峡大学 2016-10-26 CN disclosed