Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.79 |
| ▸ | LCK | P06239 | 4/20 | 0.56 |
| ▸ | JAK3 | P52333 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096707 | 1.00 | BTK (0.79) | BTKLCKJAK3EGFR | |
| SCHEMBL16764176 | 0.89 | BTK (0.79) | BTKLCKJAK3EGFR | |
| SCHEMBL16763641 | 0.89 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16764178 | 0.89 | BTK (0.79) | BTKLCKJAK3EGFR | |
| SCHEMBL16763644 | 0.89 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16764181 | 0.88 | BTK (0.71) | BTKLCKJAK3EGFR | |
| SCHEMBL16764183 | 0.88 | BTK (0.71) | BTKLCKJAK3EGFR | |
| SCHEMBL16801985 | 0.85 | BTK (0.66) | BTKLCKJAK3EGFR | |
| SCHEMBL13052205 | 0.85 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL894662 | 0.85 | BTK (0.59) | BTKLCKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-B | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-105960404-A | Inhibitors of bruton's tyrosine kinase | 药品循环有限责任公司 | 2016-09-21 | — | — | CN | disclosed |