Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28295231 | 0.84 | TDP1 (0.45) | TDP1CHRM2CHRM1OPRD1MEN1 | |
| Tert-Butyl Formate SCHEMBL27615779 | 0.83 | TDP1 (0.41) | TDP1CHRM2CHRM1HRH3OPRD1 | |
| Tert-Butyl Formate SCHEMBL27787993 | 0.82 | TDP1 (0.39) | TDP1CHRM2CHRM1HRH3OPRD1 | |
| Tert-Butyl Formate SCHEMBL27742763 | 0.79 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28331255 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28092916 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27473155 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27606011 | 0.76 | TDP1 (0.65) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28256721 | 0.76 | TDP1 (0.65) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27722006 | 0.76 | TDP1 (0.65) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110354128-A | Pyrimidine FGFR4 inhibitors | 卫材R&D管理有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-105899490-B | Pyrimidine FGFR4 Inhibitors | 卫材R&D管理有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105899490-A | Pyrimidine fgfr4 inhibitors | 卫材R&D管理有限公司 | 2016-08-24 | — | — | CN | disclosed |