Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28096891 | 0.84 | TDP1 (0.46) | TDP1OPRD1CHRM2CHRM1MEN1 | |
| Tert-Butyl Formate SCHEMBL27615779 | 0.79 | TDP1 (0.41) | TDP1OPRD1CHRM2CHRM1 | |
| Tert-Butyl Formate SCHEMBL27742763 | 0.78 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28092916 | 0.77 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28331255 | 0.77 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27473155 | 0.77 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27615962 | 0.77 | TDP1 (0.50) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28070752 | 0.77 | TDP1 (0.50) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27606011 | 0.75 | TDP1 (0.65) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27722006 | 0.75 | TDP1 (0.65) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088100-A | Pyrimidone derivatives as CDC7 inhibitor | 癌症研究科技有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106458985-B | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2019-05-03 | — | — | CN | disclosed |