SCHEMBL28096983

SCHEMBL28096983

Cc1cc(C)cc(-c2cccc3nn(-c4cc(C)cc(C)c4)nc23)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.36
RAB9A P51151 7/20 0.36
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PARP1 P09874 1/20 0.36
MCL1 Q07820 1/20 0.33
LMNA P02545 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27491076 0.80 NPC1 (0.50) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL30418276 0.79 NPC1 (0.44) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL28096984 0.77 KDM4E (0.58) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL28395541 0.73 KDM4E (0.59) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL1643503 0.72 ENPP1 (0.41) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL13299346 0.71 KDM4E (0.65) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL28052765 0.70 MAPT (0.43) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL29190939 0.69 NPC1 (0.39) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL4786435 0.69 MAPK1 (0.45) NPC1KDM4EALDH1A1HPGDMAPT
SCHEMBL8645604 0.68 COMT (0.39) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339191-B Water absorbency resin composition and the laminated body employing this water absorbency resin composition 大赛璐-湛新株式会社 2016-08-10 CN disclosed