Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650078 | 0.91 | KDM4E (0.37) | TSHRALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL8860719 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EGAAHRH3 | |
| SCHEMBL28139131 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EGAAHRH3 | |
| SCHEMBL28153635 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EGAAHRH3 | |
| SCHEMBL24661180 | 0.78 | SMN1; SMN2 (0.45) | TSHRALDH1A1SPHK1MAPTCYP2D6 | |
| SCHEMBL27780419 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAKCNA3HRH3 | |
| SCHEMBL27678892 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAKCNA3HRH3 | |
| SCHEMBL24661186 | 0.78 | SMN1; SMN2 (0.45) | TSHRALDH1A1SPHK1MAPTCYP2D6 | |
| SCHEMBL4550289 | 0.78 | SMN1; SMN2 (0.45) | TSHRALDH1A1SPHK1MAPTCYP2D6 | |
| SCHEMBL27930049 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAKCNA3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-A | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2016-08-31 | — | — | CN | disclosed |