Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638666 | 0.91 | KMT2A (0.61) | TDP1KMT2AMEN1POLBCA12 | |
| SCHEMBL3919215 | 0.87 | TDP1 (0.71) | TDP1KMT2ACA12CA7CA9 | |
| SCHEMBL27032917 | 0.86 | CA12 (0.55) | TDP1KMT2AMEN1CA12CA7 | |
| SCHEMBL2580651 | 0.85 | KMT2A (0.56) | TDP1KMT2AMEN1POLBCA12 | |
| SCHEMBL20830632 | 0.84 | KMT2A (0.52) | TDP1KMT2AMEN1POLBCA12 | |
| SCHEMBL27032841 | 0.83 | CYP3A4 (0.59) | TDP1KMT2AMEN1POLBCA12 | |
| SCHEMBL9191891 | 0.82 | ALDH1A1 (0.48) | KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL27032834 | 0.82 | TDP1 (0.52) | TDP1KMT2AMEN1POLBCA12 | |
| SCHEMBL8104907 | 0.81 | MEN1 (0.46) | TDP1KMT2AMEN1POLBLMNA | |
| SCHEMBL7660920 | 0.80 | KMT2A (0.49) | TDP1KMT2AMEN1POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106110116-A | Chinese medicine composition containing Radix Helicteris and preparation method thereof | 广西万德药业有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106075229-A | A kind of Chinese medicinal composition preparation treating anemopyretic cold | 广西万德药业有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105999166-A | Formula and preparation method of traditional Chinese medicine for treating chilblain | 三峡大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-105998977-A | Anti-cold medicine preparation | 广西万德药业有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105963603-A | Cold medicine and preparation method thereof | 广西万德药业有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105902914-A | Traditional Chinese medicine composition for treating wind-heat type common cold and preparation method thereof | 广西万德药业有限公司 | 2016-08-31 | — | — | CN | disclosed |