Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707996 | 0.86 | MMP2 (0.47) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL27406586 | 0.85 | MMP2 (0.53) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL27406587 | 0.85 | MMP2 (0.53) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL8389168 | 0.85 | MMP2 (0.53) | MEN1KMT2AMCL1MMP2MAPT | |
| Hydrochloric Acid SCHEMBL27433857 | 0.84 | MMP2 (0.46) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL4421079 | 0.84 | MMP2 (0.46) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL4421076 | 0.84 | MMP2 (0.46) | MEN1KMT2AMCL1MMP2MAPT | |
| Hydrochloric Acid SCHEMBL29565420 | 0.83 | MMP2 (0.51) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL5014650 | 0.83 | MMP2 (0.54) | MEN1KMT2AMCL1MMP2MAPT | |
| SCHEMBL5014651 | 0.83 | MMP2 (0.54) | MEN1KMT2AMCL1MMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-A | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2016-08-31 | — | — | CN | disclosed |