Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | PI4KA | P42356 | 5/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.46 |
| ▸ | AHCY | P23526 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516432 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL7436925 | 0.76 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL11222112 | 0.75 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL27502504 | 0.73 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL4438894 | 0.72 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL4438238 | 0.72 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL30544745 | 0.71 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL2638103 | 0.71 | ADORA2A (0.73) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL5033136 | 0.71 | ADORA2A (0.73) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL13731483 | 0.71 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530048-B | Adenine derivatives | 葛兰素史密丝克莱恩有限责任公司 | 2016-09-14 | — | — | CN | disclosed |