Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709430 | 1.00 | MEN1 (0.66) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL13295633 | 0.97 | MEN1 (0.63) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2675406 | 0.90 | HPGD (0.61) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL586122 | 0.90 | HPGD (0.61) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12222597 | 0.90 | HPGD (0.61) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL28263415 | 0.90 | HPGD (0.64) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2728409 | 0.89 | MEN1 (0.68) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3608462 | 0.89 | MEN1 (0.68) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL40057 | 0.89 | MEN1 (0.64) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3321211 | 0.89 | MEN1 (0.68) | MEN1ALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106520719-B | A kind of ω of S type-transaminase ATA-W12 and its gene and application | 华东理工大学 | 2019-06-07 | — | — | CN | claimed |
| CN-107573278-B | A kind of preparation method of pharmaceutical intermediate N-BOC-3- piperidones | 深圳市宏辉浩医药科技有限公司 | 2018-05-01 | — | — | CN | claimed |
| CN-106520719-B | A kind of ω of S type-transaminase ATA-W12 and its gene and application | 华东理工大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-107573278-B | A kind of preparation method of pharmaceutical intermediate N-BOC-3- piperidones | 深圳市宏辉浩医药科技有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-107574194-A | The method that living things catalysis prepares the hydroxy piperidine of (R) 1 N benzene methoxycarbonyl group 3 | 上海合全药物研发有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106520719-A | S-shaped omega-transaminase ATA-W12 as well as gene and application thereof | 华东理工大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-105949113-A | Method for efficiently synthesizing 1-Boc-3-piperidone | 苏州艾缇克药物化学有限公司 | 2016-09-21 | — | — | CN | disclosed |