Sugi Predict

Sugi Predict / Compounds / SCHEMBL2728409

SCHEMBL2728409

SCHEMBL2728409

CC(=O)C1CCCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.68
▸ ALDH1A1 P00352 1/20 0.68
▸ MAPT P10636 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ HPGD P15428 1/20 0.59
▸ EPHX1 P07099 1/20 0.49
▸ RECQL P46063 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.45
▸ ABL1 P00519 1/20 0.44
▸ RIN1 Q13671 1/20 0.44
▸ USP2 O75604 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ HSD11B1 P28845 1/20 0.43
▸ PREP P48147 1/20 0.43
▸ GLS O94925 1/20 0.43
▸ USP30 Q70CQ3 1/20 0.43
▸ NR1H2 P55055 1/20 0.42
▸ BACE1 P56817 2/20 0.42
▸ CTSD P07339 1/20 0.42
▸ PTPN2 P17706 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3608462 1.00 MEN1 (0.68) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL3321211 1.00 MEN1 (0.68) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL21954154 0.95 MEN1 (0.63) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL845563 0.90 HPGD (0.62) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL13804048 0.90 HPGD (0.62) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL10233234 0.90 HPGD (0.62) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL27709430 0.89 MEN1 (0.66) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL28097167 0.89 MEN1 (0.66) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL24011078 0.88 ALDH1A1 (0.54) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL25596826 0.88 MEN1 (0.61) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608821-A1 PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS Duke Street Bio Limited (GB) 2025-09-03 — — EP disclosed
WO-2025130765-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) 2025-06-26 — — WO disclosed
CN-118147098-B Leucine dehydrogenase mutant and application thereof in chiral nitrogen heterocyclic amine synthesis 江南大学 2025-04-25 — — CN disclosed
WO-2024115465-A1 PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS Duke Street Bio Limited (GB) 2024-06-06 — — WO disclosed
WO-2024115465-A1 PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS Duke Street Bio Limited (GB) 2024-06-06 — — WO disclosed
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 — — US disclosed
US-20230295113-A1 NLRP3 MODULATORS ZOMAGEN BIOSCIENCES LTD 2023-09-21 — — US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 — — EP disclosed
CN-112262139-B Aminopyrrolotriazines as kinase inhibitors 百时美施贵宝公司 2023-07-25 — — CN disclosed
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC 2023-05-11 — — US disclosed
EP-2066630-A1 PIPERIDINE DERIVATIVES Pfizer Products Incorporated (US) 2009-06-10 — — EP disclosed
EP-1844050-B1 PYRROLOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASE VERTEX PHARMA (US) 2009-01-14 — — EP disclosed
US-20080275085-A1 Piperidine derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 — — US disclosed
US-20080275085-A1 Piperidine derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 — — US disclosed
EP-1966139-A1 ASPARTIC PROTEASE INHIBITORS Vitae Pharmaceuticals, Inc. (US) 2008-09-10 — — EP disclosed
WO-2008023258-A1 PIPERIDINE DERIVATIVES PFIZER PRODUCTS INC. (US) 2008-02-28 — — WO disclosed
US-20070179126-A1 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof SANOFI-AVENTIS (FR) 2007-08-02 — — US disclosed
US-20070179126-A1 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof SANOFI-AVENTIS (FR) 2007-08-02 — — US disclosed
WO-2007070201-A1 ASPARTIC PROTEASE INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-06-21 — — WO disclosed
US-20070004762-A9 Pyrrolopyrimidines useful as inhibitors of protein kinase VERTEX PHARMACEUTICALS INCORPORATED 2007-01-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004762-A9 Pyrrolopyrimidines useful as inhibitors of protein kinase PRKDC, MAP3K20, MAP3K5 MEN1 2868/4885ALDH1A1 3777/4885MAPT 1300/4885
US-20080275085-A1 Piperidine derivative and use thereof TACR2, TACR1, PRLHR MEN1 1884/4885ALDH1A1 3412/4885MAPT 4330/4885
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF MYC, MYCBP, FOXO1 MEN1 1652/4885ALDH1A1 3501/4885MAPT 2576/4885
US-20230295113-A1 NLRP3 MODULATORS NLRP3, NLRP1, NOD1 MEN1 4787/4885ALDH1A1 2633/4885MAPT 382/4885
US-20070179126-A1 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof UGT2B7, PKD2, CYP2C19 MEN1 990/4885ALDH1A1 1008/4885MAPT 645/4885
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS YTHDF1, YTHDF3, YTHDF2 MEN1 3143/4885ALDH1A1 4553/4885MAPT 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.