Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28185274 | 0.96 | CA1 (0.42) | CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL3392168 | 0.95 | — | — | |
| Bicarbonate SCHEMBL2217045 | 0.95 | CA1 (0.50) | CA1CA2CA9FFAR3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL17746891 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28220084 | 0.92 | CA1 (0.39) | CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL10680464 | 0.91 | CA1 (0.33) | CA1CA2CA9FFAR3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28906254 | 0.91 | CA1 (0.33) | CA1CA2CA9FFAR3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10680451 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL27705335 | 0.91 | CA1 (0.33) | CA1CA2CA9FFAR3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16949961 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364189-B | Refined synthesis gas becomes the integrated processes of oxygen-containing organic compound with bioconversion | 赛纳塔生物有限公司 | 2016-08-24 | — | — | CN | disclosed |