Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28097261 | 0.95 | CA1 (0.46) | CA1CA2CA9FFAR3ALDH1A1 | |
| Bicarbonate SCHEMBL27686758 | 0.95 | CA1 (0.46) | CA1CA2CA9FFAR3ALDH1A1 | |
| SCHEMBL7793 | 0.95 | — | — | |
| SCHEMBL31313730 | 0.95 | CA1 (0.40) | CA1CA2CA9FFAR3ALDH1A1 | |
| Benzene SCHEMBL4412824 | 0.91 | CA1 (0.42) | CA1CA2CA9ALDH1A1TSHR | |
| Bicarbonate SCHEMBL28185274 | 0.91 | CA1 (0.42) | CA1CA2CA9 | |
| Benzene SCHEMBL7906078 | 0.91 | CA1 (0.42) | CA1CA2CA9ALDH1A1TSHR | |
| Fluoride SCHEMBL23213374 | 0.90 | CA1 (0.36) | CA1CA2CA9FFAR3ALDH1A1 | |
| SCHEMBL3141792 | 0.90 | — | — | |
| Ammonia Solution, Strong SCHEMBL3392168 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729991-A | Method for producing 2-time dehydrated superabsorbent polymer for superabsorbent recycled polymer, and method for producing superabsorbent recycled polymer | 尤妮佳股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023190183-A1 | CROSSLINKED RESIN PARTICLES AND METHOD FOR PRODUCING SAME | 株式会社カネカ | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190184-A1 | THERMOPLASTIC RESIN COMPOSITION | 株式会社カネカ | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190185-A1 | THERMOPLASTIC RESIN COMPOSITION | 株式会社カネカ | 2023-10-05 | — | — | WO | disclosed |
| CN-116438120-A | Aromatic diol compound, diepoxide compound, polymer prepared from such compound, and process for producing the same | SWIMC有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022075403-A1 | ONE OR MORE HLA GENE PRIMERS | 国立研究開発法人国立国際医療研究センター | 2022-04-14 | — | — | WO | disclosed |
| EP-2215144-B1 | COPOLYMERS COMPRISING A TRIMETHYLENE CARBONATE AND POLY(TRIMETHYLENE ETHER) GLYCOLS | DU PONT (US) | 2011-07-13 | — | — | EP | disclosed |
| US-7790834-B2 | Copolymers comprising trimethylene carbonate and poly(trimethylene ether) glycols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| EP-2215144-A1 | COPOLYMERS COMPRISING A TRIMETHYLENE CARBONATE AND POLY(TRIMETHYLENE ETHER) GLYCOLS | E. I. du Pont de Nemours and Company (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009070578-A1 | COPOLYMERS COMPRISING A TRIMETHYLENE CARBONATE AND POLY(TRIMETHYLENE ETHER) GLYCOLS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-04 | — | — | WO | disclosed |
| US-20040024318-A1 | Method for assessing myocardial angiogenesis | GENERAL ELECTRIC COMPANY | 2004-02-05 | — | — | US | disclosed |
| US-20040022729-A1 | Method for binding molecular agents to angiogencic blood vessels | GENERAL ELECTRIC COMPANY | 2004-02-05 | — | — | US | disclosed |
| WO-2004010868-A2 | METHOD FOR BINDING MOLECULAR AGENTS TO ANGIOGENCIC BLOOD VESSELS | GENERAL ELECTRIC COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
| WO-2004010841-A2 | METHOD FOR ASSESSING MYOCARDIAL ANGIOGENESIS | GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) | 2004-02-05 | — | — | WO | disclosed |
| WO-2004011036-A1 | METHOD FOR ASSESSING CAPILLARY PERMEABILITY | GENERAL ELECTRIC COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
| US-5164318-A | Requiring bound-free separation | HITACHI, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-4842995-A | Diagnostic method for the evaluation of clinical parameters by direct collection of biological materials and device for its accomplishment | BOEHRINGER BIOCHEMIA ROBIN, S.P.A. (IT) | 1989-06-27 | — | — | US | disclosed |
| EP-0041426-B1 | COUPLED PRODUCT BETWEEN A LECTIN AND A SPECIFIC LIGAND, OBTENTION AND USE IN THE BIOLOGICAL FIELD | INSTITUT PASTEUR (FR) | 1985-11-13 | — | — | EP | disclosed |
| US-4526871-A | Immobilizing substance having binding affinity for biological substance to be determined, incubating with substance to be determined, incubating with conjugate of lectin specific ligand in solution specific to lectin | INSTITUT PASTEUR (FR) | 1985-07-02 | — | — | US | disclosed |
| EP-0041426-A1 | Coupled product between a lectin and a specific ligand, obtention and use in the biological field | INSTITUT PASTEUR (FR) | 1981-12-09 | — | — | EP | disclosed |