Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097357 | 0.91 | KMT2A (0.41) | MAPK14KMT2AMEN1POLBNR3C1 | |
| SCHEMBL14876216 | 0.77 | KDM4E (0.46) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14875835 | 0.76 | MMP1 (0.47) | MAPK14KMT2AALDH1A1 | |
| SCHEMBL14876084 | 0.74 | KMT2A (0.51) | KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14876520 | 0.73 | KMT2A (0.50) | MAPK14KMT2AMEN1ALDH1A1 | |
| SCHEMBL14883145 | 0.72 | CTSA (0.45) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14875741 | 0.72 | CNR2 (0.42) | CNR2 | |
| SCHEMBL14875679 | 0.71 | SMN1; SMN2 (0.53) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14882792 | 0.69 | GRM4 (0.43) | KMT2AMEN1NR3C1L3MBTL1ALDH1A1 | |
| SCHEMBL14875626 | 0.69 | RXFP1 (0.47) | KMT2AMEN1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958521-B | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | 弗·哈夫曼-拉罗切有限公司 | 2016-10-19 | — | — | CN | disclosed |