Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816006 | 0.90 | TSHR (0.43) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28097630 | 0.85 | TSHR (0.46) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28047452 | 0.85 | TSHR (0.46) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28047407 | 0.84 | TSHR (0.44) | TSHRKDM4EAKR1B1 | |
| SCHEMBL28050988 | 0.84 | TSHR (0.48) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28097628 | 0.84 | TSHR (0.44) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28144559 | 0.81 | TSHR (0.47) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28153750 | 0.81 | TSHR (0.42) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28047464 | 0.81 | CYP2C9 (0.50) | TSHRKDM4ECYP2C9HIF1AHSD17B10 | |
| SCHEMBL27994728 | 0.80 | TSHR (0.55) | TSHRKDM4EPTPN1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271571-B | Tetrazolinone compound and use thereof | 住友化学株式会社 | 2017-07-07 | — | — | CN | disclosed |
| CN-104245689-B | Terazololine-one compound and its purposes as insecticide | 住友化学株式会社 | 2017-06-06 | — | — | CN | disclosed |
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104684908-B | Terazololine-one compound and the purposes as insecticide thereof | 住友化学株式会社 | 2016-09-28 | — | — | CN | disclosed |