Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097517 | 0.90 | TSHR (0.44) | TSHRKDM4EFOLH1KMOPTPN1 | |
| SCHEMBL27994551 | 0.86 | TSHR (0.43) | TSHRKDM4EFOLH1PTPN1CYP2C9 | |
| SCHEMBL27994771 | 0.86 | TSHR (0.43) | TSHRKDM4EFOLH1PTPN1CYP2C9 | |
| SCHEMBL27994464 | 0.85 | TSHR (0.43) | TSHRKDM4EAKR1B1SLC16A3 | |
| SCHEMBL28815926 | 0.85 | TSHR (0.43) | TSHRKDM4EFOLH1PTPN1CYP2C9 | |
| SCHEMBL27994739 | 0.82 | TSHR (0.40) | TSHRKDM4EPTPN1CYP2C9HIF1A | |
| SCHEMBL28050939 | 0.81 | TSHR (0.53) | TSHRKDM4EFOLH1PTPN1CYP2C9 | |
| SCHEMBL27999461 | 0.81 | CASP6 (0.42) | TSHRAKR1C3AKR1C2CDC25B | |
| SCHEMBL28144559 | 0.79 | TSHR (0.47) | TSHRKDM4EFOLH1KMOPTPN1 | |
| SCHEMBL28047452 | 0.78 | TSHR (0.46) | TSHRKDM4EFOLH1PTPN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |
| CN-104822666-A | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL CO | 2015-08-05 | — | — | CN | disclosed |
| CN-104684908-A | Tetrazolinone compounds and their use as pesticides | SUMITOMO CHEMICAL CO | 2015-06-03 | — | — | CN | disclosed |
| CN-104271571-A | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL CO | 2015-01-07 | — | — | CN | disclosed |
| CN-104245689-A | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL CO | 2014-12-24 | — | — | CN | disclosed |