SCHEMBL28097556

SCHEMBL28097556

Cc1ccc(C(=O)O)c(-c2cccc(Cl)c2CBr)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.39
FABP4 P15090 2/20 0.39
FABP3 P05413 1/20 0.39
NOTUM Q6P988 4/20 0.37
TSHR P16473 2/20 0.36
AKR1B1 P15121 1/20 0.36
TRPM4 Q8TD43 1/20 0.36
PBRM1 Q86U86 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
FTO Q9C0B1 2/20 0.35
TTR P02766 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
PTGS2 P35354 2/20 0.35
AKR1C3 P42330 2/20 0.35
AKR1B10 O60218 1/20 0.35
ABCB11 O95342 1/20 0.35
CHRM1 P11229 1/20 0.35
FABP2 P12104 1/20 0.35
RXRA P19793 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28097579 0.88 MYC (0.45) MYCFABP4FABP3NOTUMKMT2A
SCHEMBL28097596 0.86 MYC (0.40) MYCFABP4KMT2AMEN1ALDH1A1
SCHEMBL28203200 0.85 MYC (0.39) MYCPTGS2MAPK1ALDH1A1LMNA
SCHEMBL28202955 0.82 CA12 (0.44) MYCFABP4FABP3ALDH1A1MAPT
SCHEMBL28097567 0.82 MYC (0.40) MYCKMT2AMAPK1ALDH1A1LMNA
SCHEMBL28829363 0.82 KMT2A (0.44) MYCFABP4FABP3NOTUMTSHR
SCHEMBL28014917 0.75 MYC (0.47) MYCFABP4FABP3KMT2APTGS2
SCHEMBL28019290 0.75 MYC (0.38) MYCKMT2AMAPK1ALDH1A1LMNA
SCHEMBL28069046 0.74 MYC (0.44) MYCFABP4AKR1B1KMT2AMEN1
SCHEMBL28122101 0.74 HAAO (0.38) MYCNOTUMKMT2AAKR1C3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104884442-B Terazololine-one compound and application thereof 住友化学株式会社 2016-11-02 CN disclosed