SCHEMBL28097579

SCHEMBL28097579

Cc1cccc(-c2c(C(=O)O)ccc(C)c2C(=O)O)c1CBr

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.45
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
TYMS P04818 1/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MCL1 Q07820 1/20 0.35
NOTUM Q6P988 1/20 0.35
FOLH1 Q04609 1/20 0.34
FABP4 P15090 2/20 0.33
HAAO P46952 1/20 0.33
FABP3 P05413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28097596 0.89 MYC (0.40) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28097556 0.88 MYC (0.39) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28203200 0.88 MYC (0.39) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28097567 0.86 MYC (0.40) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28202955 0.86 CA12 (0.44) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28014917 0.78 MYC (0.47) MYCALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL28019290 0.78 MYC (0.38) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28069046 0.77 MYC (0.44) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL8384754 0.77 HAAO (0.38) MYCALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28122101 0.77 HAAO (0.38) MYCALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104884442-B Terazololine-one compound and application thereof 住友化学株式会社 2016-11-02 CN disclosed