Pyrazon

Pyrazon

SCHEMBL28097864

Nc1cnn(-c2ccccc2)c(=O)c1Cl.O=[N+]([O-])c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.54
MAPT P10636 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HTT P42858 2/20 0.54
NPC1 O15118 2/20 0.54
ALDH1A1 P00352 2/20 0.54
MITF O75030 1/20 0.54
S1PR4 O95977 1/20 0.54
THRB P10828 1/20 0.54
XBP1 P17861 1/20 0.54
S1PR1 P21453 1/20 0.54
PAX8 Q06710 1/20 0.54
CYP1A2 P05177 3/20 0.51
CYP2C9 P11712 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2D6 P10635 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazon SCHEMBL1858918 0.86 RAB9A (0.70) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL53824 0.86 RAB9A (0.70) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL16899678 0.81 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL27859399 0.81 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HTTNPC1
Aclonifen SCHEMBL7585432 0.77 MEN1 (0.66) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL7584298 0.76 SMN1; SMN2 (0.42) RAB9AMAPTSMN1; SMN2HTTNPC1
SCHEMBL10813878 0.74 MAPT (0.53) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL28074556 0.74 RAB9A (0.54) RAB9AMAPTSMN1; SMN2HTTNPC1
SCHEMBL10818322 0.74 RAB9A (0.63) RAB9AMAPTSMN1; SMN2HTTNPC1
Pyrazon SCHEMBL27376161 0.73 RAB9A (0.52) RAB9AMAPTSMN1; SMN2HTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105939605-A Methods for controlling weeds using formulations containing fluthiacet-methyl and hppd herbicides FMC有限公司 2016-09-14 CN disclosed