Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028593 | 0.95 | GAA (0.52) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Hydrogen Peroxide SCHEMBL28104512 | 0.95 | GAA (0.55) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL29387462 | 0.95 | GAA (0.55) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL39866 | 0.95 | GAA (0.55) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Ethylene Glycol SCHEMBL551090 | 0.94 | GAA (0.51) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Ethylene Glycol SCHEMBL8407093 | 0.94 | GAA (0.51) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL28324794 | 0.94 | GAA (0.57) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Methane SCHEMBL28345434 | 0.94 | GAA (0.54) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL5491694 | 0.94 | GAA (0.54) | GAAKMT2AMEN1CYP1A2CYP2C9 | |
| Ethylene SCHEMBL4043660 | 0.93 | GAA (0.52) | GAAKMT2AMEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102538-B | Stabilisation polycarbonate Alloys containing post-consumer recycled plastic | 沙特基础全球技术有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107429050-B | Product with reduced absorbance | 沙特基础工业全球技术有限公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-104136535-B | Thermoplastic polycarbonate copolymer compositions, methods of making them, and articles thereof | 沙特基础全球技术有限公司 | 2016-08-24 | — | — | CN | disclosed |