Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.58 |
| ▸ | RET | P07949 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568255 | 0.91 | KIT (0.64) | KITRETKDREGFRENPP1 | |
| SCHEMBL182873 | 0.78 | PIK3CD (0.60) | KITRETENPP1 | |
| SCHEMBL6181412 | 0.76 | EGFR (0.63) | KITRETKDREGFRATM | |
| SCHEMBL5569432 | 0.76 | KIT (0.69) | KITRETKDREGFRENPP1 | |
| SCHEMBL4782102 | 0.76 | WHR1 (0.61) | KITRETKDREGFRATM | |
| SCHEMBL2126095 | 0.75 | EGFR (0.61) | KITKDREGFRFGFR1FLT1 | |
| SCHEMBL2125179 | 0.75 | EGFR (0.61) | KITRETKDREGFRFLT1 | |
| SCHEMBL182424 | 0.75 | PIK3CD (0.60) | KITENPP1 | |
| SCHEMBL295984 | 0.74 | WHR1 (0.50) | KITRETKDREGFR | |
| SCHEMBL26098937 | 0.74 | KIT (0.56) | KITRETKDREGFRENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045980-A | Quinazoline derivative and preparation method thereof | 江苏开放大学 | 2016-10-26 | — | — | CN | disclosed |