SCHEMBL5568255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28098004	0.91	KIT (0.58)	KITKDRRETEGFRATM
	SCHEMBL6181412	0.84	EGFR (0.63)	KITKDRRETEGFRATM
	SCHEMBL5569432	0.84	KIT (0.69)	KITKDRRETEGFRENPP1
	SCHEMBL4782102	0.84	WHR1 (0.61)	KITKDRRETEGFRATM
	SCHEMBL2126095	0.83	EGFR (0.61)	KITKDREGFRSRCLCK
	SCHEMBL2125179	0.83	EGFR (0.61)	KITKDRRETEGFRSRC
	SCHEMBL5568252	0.81	PIK3CD (0.56)	KITKDREGFRENPP1MAPK14
	SCHEMBL27734225	0.80	RET (0.44)	KITKDRRETEGFRABL1
	SCHEMBL15516134	0.78	KIT (1.00)	KITKDRRETEGFRENPP1
	SCHEMBL295421	0.78	WHR1 (0.52)	KDRRETEGFRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.