Benzonitrile

Benzonitrile

SCHEMBL28098033

CO.N#Cc1ccccc1

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.82
MAOB P27338 4/20 0.52
MAOA P21397 3/20 0.52
ALDH1A1 P00352 3/20 0.50
CYP2A6 P11509 2/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
HDAC8 Q9BY41 2/20 0.46
APP P05067 1/20 0.45
ENPP2 Q13822 2/20 0.44
MMP3 P08254 1/20 0.44
MAPT P10636 2/20 0.44
NOS3 P29474 2/20 0.43
NOS1 P29475 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzonitrile SCHEMBL11740588 0.94 TSHR (0.93) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL11737166 0.94 TSHR (0.93) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL27895262 0.91 TSHR (0.88) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL2154015 0.91 TSHR (0.88) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL6640 0.91
Benzonitrile SCHEMBL11044747 0.91
Benzonitrile SCHEMBL9464940 0.91 TSHR (1.00) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL30929383 0.91 TSHR (1.00) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL27793280 0.91 TSHR (1.00) TSHRMAOBMAOAALDH1A1CYP2A6
Benzonitrile SCHEMBL21752925 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116899585-A Co-based catalyst for nitrile hydrogenation and preparation method and application thereof 中海油天津化工研究设计院有限公司 2023-10-20 CN disclosed
CN-217699096-U O-methoxy cyanophenyl synthesizer 濮阳市远东化工有限公司 2022-11-01 CN disclosed
CN-217699096-U O-methoxy cyanophenyl synthesizer 濮阳市远东化工有限公司 2022-11-01 CN disclosed
CN-107043454-B Epoxy group-amine additives, resin combination, cementing agent, the carbon fiber and fiber reinforced composite material for being coated with cementing agent 株式会社大赛璐 2019-08-20 CN disclosed
CN-107709401-A Solidification compound and formed body 株式会社大赛璐 2018-02-16 CN disclosed
CN-107709400-A Solidification compound 株式会社大赛璐 2018-02-16 CN disclosed
CN-104995255-B Colored curable composition and use thereof 富士胶片株式会社 2017-11-14 CN disclosed
CN-107148676-A Solar cell module and its manufacture method 材料概念有限公司 2017-09-08 CN disclosed
CN-107043454-A Epoxy radicals amine additives, resin combination, cementing agent, the carbon fiber and fiber reinforced composite material for being coated with cementing agent 株式会社大赛璐 2017-08-15 CN disclosed
CN-104284916-B Epoxy-amine adduct, resin composition, sizing agent, carbon fiber coated with sizing agent, and fiber-reinforced composite material 株式会社大赛璐 2016-12-14 CN disclosed
CN-104321385-B Hardening resin composition and solidfied material, sealant and optical semiconductor device 株式会社大赛璐 2016-08-24 CN disclosed