Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493285 | 0.98 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| SCHEMBL7782987 | 0.98 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| SCHEMBL6250353 | 0.98 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| Hydrochloric Acid SCHEMBL3048944 | 0.95 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| Hydrochloric Acid SCHEMBL22164454 | 0.95 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| Hydrochloric Acid SCHEMBL6231526 | 0.95 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KIF11KMT2A | |
| SCHEMBL10633496 | 0.88 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1CA14KIF11 | |
| SCHEMBL8894673 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA14KIF11CA1 | |
| SCHEMBL18870139 | 0.80 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1KMT2AALOX15BLM | |
| SCHEMBL16775768 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1KIF11KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104356020-B | A kind of amide groups ester and synthetic method, application | 郁维铭 | 2016-08-24 | — | — | CN | disclosed |