Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137848 | 0.82 | TSHR (0.52) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL28967097 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL29462390 | 0.77 | TSHR (0.52) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL164458 | 0.77 | TSHR (0.52) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL16178467 | 0.76 | PTPN1 (0.42) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL718733 | 0.76 | TP53 (0.48) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL689815 | 0.74 | PTPN1 (0.41) | ALDH1A1CYP3A4SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL1544963 | 0.74 | PTGDR2 (0.36) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL8802741 | 0.74 | CYP3A4 (0.48) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL27713326 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1TSHRCYP3A4SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222614-A1 | HETEROCYCLIC GSPT1 DEGRADATION AGENT | 北京诺诚健华医药科技有限公司 | 2024-10-31 | — | — | WO | disclosed |
| CN-118619880-A | Low-cost and environment-friendly method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2024-09-10 | — | — | CN | disclosed |
| CN-117486844-A | Green synthesis method of photo-promoted quaternary carbon center-containing phthalide derivative | 重庆医科大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117384201-A | 1-alkenyl indole compound and preparation method thereof | 鲁东大学 | 2024-01-12 | — | — | CN | disclosed |
| US-20230357214-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | PHENEX PHARMACEUTICALS AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | US | disclosed |
| US-20230357214-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | PHENEX PHARMACEUTICALS AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | US | disclosed |
| CN-113416166-B | Method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2022-08-05 | — | — | CN | disclosed |
| CN-113416166-A | Method for preparing 4-hydroxyquinoline-2 (1H) -ketone compound | 浙江外国语学院 | 2021-09-21 | — | — | CN | disclosed |
| US-20210147398-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | PHENEX-FXR GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| CN-105859725-A | 5,10-dihydroindolo[3,2-b]indole derivative synthesis method | 天津大学 | 2016-08-17 | — | — | CN | disclosed |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ALDH1A1 401/4885TSHR 3644/4885CYP3A4 1909/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | ALDH1A1 1480/4885TSHR 4692/4885CYP3A4 3918/4885 |
| US-20210147398-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | NR1H2, NR1H3, NR1H4 | ALDH1A1 3993/4885TSHR 424/4885CYP3A4 823/4885 |
| US-20230357214-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | NR1H2, NR1H3, NR1H4 | ALDH1A1 3993/4885TSHR 424/4885CYP3A4 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.