Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462390 | 1.00 | TSHR (0.52) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL3274518 | 0.84 | MCL1 (0.51) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL166558 | 0.82 | TSHR (0.52) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL28967097 | 0.81 | SMN1; SMN2 (0.56) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28847255 | 0.80 | TSHR (0.50) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL5360561 | 0.79 | CYP3A4 (0.48) | TSHRCYP3A4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL8388704 | 0.79 | AR (0.56) | CYP3A4ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL4168666 | 0.79 | KDM4E (0.55) | ALDH1A1HPGDKDM4EMAOBGAA | |
| SCHEMBL20565736 | 0.79 | MAOA (0.72) | CYP3A4ALDH1A1TDP1CYP2A6HPGD | |
| SCHEMBL7050401 | 0.78 | MAOA (0.61) | CYP3A4ALDH1A1TDP1CYP2A6VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380718-B | Acylation method of aniline compound | 河南农业大学 | 2022-09-30 | — | — | CN | claimed |
| CN-114380718-A | Acylation method of aniline compound | 河南农业大学 | 2022-04-22 | — | — | CN | claimed |
| CN-114031566-A | Preparation method of stable isotope labeled diazepam internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-113549078-A | Preparation method of stable isotope labeled alprazolam and estazolam internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113549022-A | Preparation method of stable isotope labeled oxazepam internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-112920128-A | Novel method for synthesizing D5-diazepam | 成都大学 | 2021-06-08 | — | — | CN | claimed |
| CN-108640919-B | Matrine derivative and sophoridine derivative containing aryl amidine or aminoquinoline structure and preparation method thereof | 广西大学 | 2020-09-08 | — | — | CN | claimed |
| CN-106946800-B | A kind of synthetic method of -2,4 (1H, 3H)-diketone of quinazoline and its derivative | 华东师范大学 | 2019-11-15 | — | — | CN | claimed |
| CN-108640919-A | The matrine derivative and Sophoridine derivative and preparation method thereof of amidine containing aryl or aminoquinoline structure | 广西大学 | 2018-10-12 | — | — | CN | claimed |
| CN-106946800-A | A kind of synthetic method of (1H, the 3H) diketone of quinazoline 2,4 and its derivative | 华东师范大学 | 2017-07-14 | — | — | CN | claimed |
| EP-4714953-A1 | MELANOCORTIN 2-TYPE RECEPTOR ANTAGONIST | Scohia Pharma, Inc. (JP) | 2026-03-25 | — | — | EP | disclosed |
| US-12540248-B2 | Metal surface-treating agent, and metal material with coating film and method for manufacturing same | NIHON PARKERIZING CO., LTD. (JP) | 2026-02-03 | — | — | US | disclosed |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-12-04 | — | — | US | disclosed |
| EP-3927685-B1 | A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | PI INDUSTRIES LTD (IN) | 2025-10-08 | — | — | EP | disclosed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540248-B2 | Metal surface-treating agent, and metal material with coating film and method for manufacturing same | VMA21, CARM1, CROCC | TSHR 1756/4885CYP3A4 3843/4885ALOX15 2760/4885 |
| US-20250368604-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | TSHR 3558/4885CYP3A4 4677/4885ALOX15 3974/4885 |
| US-20250376443-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | TSHR 3460/4885CYP3A4 4700/4885ALOX15 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.