Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013207 | 0.81 | CYP2C19 (0.53) | CYP2C19ALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL27511141 | 0.75 | AOC3 (0.53) | RAB9ACA1ALDH1A1KMT2A | |
| SCHEMBL10618249 | 0.74 | CYP19A1 (0.42) | RAB9ACYP19A1USP2KIF11LATS1 | |
| SCHEMBL10620617 | 0.72 | CYP19A1 (0.45) | RAB9ACYP19A1USP2CYP2C19KIF11 | |
| SCHEMBL5929601 | 0.69 | CYP2C19 (0.47) | RAB9ACYP19A1USP2CYP2C19KIF11 | |
| SCHEMBL28197455 | 0.68 | MEN1 (0.50) | RAB9ACYP19A1USP2CYP2C19KIF11 | |
| SCHEMBL20710610 | 0.68 | CYP19A1 (0.48) | RAB9ACYP19A1USP2KIF11ALDH1A1 | |
| SCHEMBL2554687 | 0.68 | CYP19A1 (0.48) | RAB9ACYP19A1USP2KIF11MAP4K4 | |
| SCHEMBL22060749 | 0.67 | KIF11 (0.34) | KIF11ALDH1A1KMT2ALATS1LATS2 | |
| SCHEMBL5362887 | 0.67 | CYP19A1 (0.36) | RAB9ACYP19A1USP2CYP2C19KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476416-B | The Compounds and methods for for the treatment of hypertension | 梅迪维新技术公司 | 2016-09-21 | — | — | CN | disclosed |