Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 11/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309061 | 0.82 | CYP1A2 (0.44) | KLKB1MAP4K1 | |
| SCHEMBL27834462 | 0.79 | SMN1; SMN2 (0.40) | TEC | |
| SCHEMBL28085979 | 0.78 | EGFR (0.46) | — | |
| SCHEMBL553917 | 0.77 | MET (0.41) | KLKB1MAP4K1TEC | |
| SCHEMBL17442812 | 0.76 | KLKB1 (0.42) | KLKB1MAP4K1 | |
| SCHEMBL7274371 | 0.76 | NPC1 (0.47) | — | |
| SCHEMBL28328429 | 0.76 | TEC (0.46) | TEC | |
| SCHEMBL22276493 | 0.74 | CYP1A2 (0.41) | KLKB1MAP4K1 | |
| SCHEMBL554212 | 0.74 | KLKB1 (0.44) | KLKB1MAP4K1 | |
| Hydrochloric Acid SCHEMBL28309817 | 0.74 | KLKB1 (0.41) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-105968115-A | Quinoline compounds and preparation method thereof, and intermediate, pharmaceutical composition and application of quinoline compounds | 上海医药集团股份有限公司 | 2016-09-28 | — | — | CN | disclosed |