Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.64 |
| ▸ | HRH1 | P35367 | 12/20 | 0.64 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696312 | 0.93 | HTR6 (0.63) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL13834017 | 0.92 | HTR6 (0.62) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL13696316 | 0.92 | HTR6 (0.61) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL167305 | 0.88 | HTR6 (0.69) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL4129997 | 0.86 | HTR6 (0.69) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL169588 | 0.86 | HTR6 (0.61) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL12480215 | 0.85 | HTR6 (0.67) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL168561 | 0.85 | HTR6 (0.57) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL13834626 | 0.84 | HTR6 (0.66) | HTR6HRH1GRIN1GRIN2AGRIN2B | |
| SCHEMBL168280 | 0.83 | HTR6 (0.58) | HTR6HRH1GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476416-B | The Compounds and methods for for the treatment of hypertension | 梅迪维新技术公司 | 2016-09-21 | — | — | CN | disclosed |