SCHEMBL28098475

SCHEMBL28098475

Cc1c(F)ccc(Cc2ccc(C(=O)O)cc2C(=O)O)c1CBr

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.41
TSHR P16473 1/20 0.38
KDM4E B2RXH2 3/20 0.36
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
TTR P02766 3/20 0.34
ALB P02768 1/20 0.34
MYC P01106 1/20 0.34
EPRS1 P07814 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.33
HSD17B10 Q99714 2/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RARG P13631 1/20 0.33
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27999505 0.90 RXRA (0.40) RXRATSHRKDM4EEPHX2NR1H4
SCHEMBL27999533 0.88 RXRA (0.42) RXRATSHRKDM4EEPHX2NR1H4
SCHEMBL28834167 0.84 RXRA (0.40) RXRATSHRKDM4EEPHX2NR1H4
SCHEMBL28097628 0.83 TSHR (0.44) RXRATSHRKDM4EEPHX2NR1H4
SCHEMBL28050988 0.81 TSHR (0.48) RXRATSHRKDM4ERAB9AHSD17B10
SCHEMBL28144595 0.80 TSHR (0.47) RXRATSHRKDM4EEPHX2NR1H4
SCHEMBL28097630 0.79 TSHR (0.46) RXRATSHRKDM4ELMNARAB9A
SCHEMBL28145566 0.78 TSHR (0.38) RXRATSHRKDM4EEPHX2MYC
SCHEMBL28047452 0.76 TSHR (0.46) TSHRKDM4ELMNAMRGPRX4HSD17B10
SCHEMBL28815926 0.76 TSHR (0.43) RXRATSHRKDM4ETTRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104245689-B Terazololine-one compound and its purposes as insecticide 住友化学株式会社 2017-06-06 CN disclosed
CN-104684908-B Terazololine-one compound and the purposes as insecticide thereof 住友化学株式会社 2016-09-28 CN disclosed
CN-104822666-B Terazololine-one compound and application thereof 住友化学株式会社 2016-09-21 CN disclosed