Benzene

Benzene

SCHEMBL28098640

CCCCC(Cl)C(C)=O.c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.45
MAPK1 P28482 1/20 0.45
ACHE P22303 1/20 0.40
BACE1 P56817 1/20 0.40
CNR2 P34972 1/20 0.40
GPR84 Q9NQS5 5/20 0.39
CA1 P00915 3/20 0.39
FFAR1 O14842 1/20 0.39
POLB P06746 1/20 0.39
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11458595 0.93
SCHEMBL254414 0.86 GPR84 (0.46) CA2GPR84CA1FFAR1MAPT
Fluorobenzene SCHEMBL28786001 0.86 CNR2 (0.42) CA2MAPK1CNR2POLBMAPT
SCHEMBL11465495 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11474694 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11466630 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11466265 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11459203 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11467060 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT
SCHEMBL11458688 0.84 GPR84 (0.50) CA2GPR84CA1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103450243-B (methyl) acrylate monomer of oligomerization cubical contraction without structure of bisphenol A and its preparation method and application 华南理工大学 2016-10-05 CN claimed