Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126658 | 0.83 | PTGDR2 (0.50) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL4666470 | 0.83 | MAPT (0.54) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL19798298 | 0.83 | L3MBTL1 (0.52) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL28098679 | 0.82 | PTGDR2 (0.54) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL10126750 | 0.82 | PTGDR2 (0.47) | L3MBTL1MAPTTHRBPTGDR2LMNA | |
| SCHEMBL10126759 | 0.82 | PTGDR2 (0.49) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL10126774 | 0.81 | PTGDR2 (0.53) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL13347985 | 0.81 | PTGDR2 (0.54) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL9925002 | 0.81 | PTGDR2 (0.52) | L3MBTL1MAPTTHRBPTGDR2CNR1 | |
| SCHEMBL927918 | 0.80 | CNR1 (0.64) | MAPTCNR1CNR2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980364-A | Bicyclic heteroaryl indole analogs useful as ROR γ modulators | 格兰马克药品股份有限公司 | 2016-09-28 | — | — | CN | disclosed |