SCHEMBL28098776

SCHEMBL28098776

CCNCCCC(CC)[SiH](OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
MEN1 O00255 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
KDM1A O60341 5/20 0.33
SAT1 P21673 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11658976 0.85 CA12 (0.38) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL11658155 0.84 CA12 (0.40) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL17784248 0.79
SCHEMBL3481789 0.77 DNM1 (0.39) TSHR
SCHEMBL27812172 0.75 DNM1 (0.37) CYP1A2
SCHEMBL17747849 0.74 C3AR1 (0.33) MEN1KMT2ATSHR
SCHEMBL17937611 0.74
SCHEMBL2928491 0.74 CYP3A4 (0.32)
SCHEMBL2867544 0.74 TSHR (0.31) TSHR
SCHEMBL6298249 0.74 DNM1 (0.41) CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102702246-B Amino-acid modified silane compound and preparation method 信越化学工业株式会社 2016-09-28 CN disclosed