Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590035 | 0.99 | MAPT (0.41) | MAPTKDM4EKMT2AMEN1PKM | |
| SCHEMBL2942317 | 0.84 | CYP1A1 (0.34) | KDM4E | |
| SCHEMBL5319098 | 0.82 | — | — | |
| SCHEMBL8986470 | 0.81 | KDM4E (0.33) | MAPTKDM4EKMT2AMEN1PKM | |
| SCHEMBL2951402 | 0.81 | PDE4A (0.36) | MAPTKDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL8038380 | 0.80 | KDM4E (0.33) | MAPTKDM4EKMT2AMEN1PKM | |
| Hydrochloric Acid SCHEMBL5537163 | 0.79 | KDM4E (0.33) | MAPTKDM4EKMT2AMEN1PKM | |
| SCHEMBL9429848 | 0.79 | MAPT (0.36) | MAPTKDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL28973039 | 0.78 | NPC1 (0.31) | TP53 | |
| SCHEMBL29148790 | 0.78 | AMY1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104327036-B | A kind of preparation method of cyclic carbonate | 中国科学院长春应用化学研究所 | 2017-03-29 | — | — | CN | disclosed |
| CN-104448283-B | A kind of preparation method of Merlon | 中国科学院长春应用化学研究所 | 2016-09-28 | — | — | CN | disclosed |