Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Methylene Chloride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28986052 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL537879 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL27731198 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL1669038 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL375460 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL27943050 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL1332597 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL8546647 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL7293016 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL18247337 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106800499-A | A kind of synthesis technique of salmeterol intermediate bromide | 上海恒晟药业有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-104327036-B | A kind of preparation method of cyclic carbonate | 中国科学院长春应用化学研究所 | 2017-03-29 | — | — | CN | disclosed |
| CN-104448283-B | A kind of preparation method of Merlon | 中国科学院长春应用化学研究所 | 2016-09-28 | — | — | CN | disclosed |