Methylene Chloride

Methylene Chloride

SCHEMBL537879

ClCCl.[Na+].[OH-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Methylene Chloride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117305024-A Method for extracting neutral characteristic aroma substances of Maotai-flavor distilled spirit vinasse by alcohol extraction method 茅台学院 2023-12-29 CN claimed
CN-117285983-A Method for extracting refined alkaline fragrant substances from Maotai-flavor distilled spirit vinasse 茅台学院 2023-12-26 CN claimed
CN-117186996-A Method for extracting refined acidic fragrant substances from Maotai-flavor distilled spirit vinasse 茅台学院 2023-12-08 CN claimed
JP-4013720-A None JP disclosed
CN-117305024-A Method for extracting neutral characteristic aroma substances of Maotai-flavor distilled spirit vinasse by alcohol extraction method 茅台学院 2023-12-29 CN disclosed
CN-117285983-A Method for extracting refined alkaline fragrant substances from Maotai-flavor distilled spirit vinasse 茅台学院 2023-12-26 CN disclosed
CN-117186996-A Method for extracting refined acidic fragrant substances from Maotai-flavor distilled spirit vinasse 茅台学院 2023-12-08 CN disclosed
CN-116873876-A Resource clean treatment method for lithium bis (fluorosulfonyl) imide separation filtrate 江苏卓邦新能源科技有限公司 2023-10-13 CN disclosed
CN-111533843-A High-performance bio-based resin and preparation method and application thereof 福建农林大学 2020-08-14 CN disclosed
CN-109600993-A Anti-EGFR antibody drug conjugates 艾伯维公司 2019-04-09 CN disclosed
CN-109563167-A ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES 艾伯维公司 2019-04-02 CN disclosed
US-5171747-A Anxiolytic agents, antidepressants DELALANDE S.A. (FR) 1992-12-15 US disclosed
JP-H0413720-A POLYCARBONATE NIPPON TELEGR & TELEPH CORP <NTT> 1992-01-17 JP disclosed
US-5036091-A Psychotropic drugs DELALANDE S.A. (FR) 1991-07-30 US disclosed
US-5036090-A Antidepressants DELALANDE S.A. (FR) 1991-07-30 US disclosed
US-4996225-A Antitumor agents FARMOS GROUP LTD. (FI) 1991-02-26 US disclosed
US-4696949-A ANTITUMOR AGENTS, ANTIESTROGENS FARMOS GROUP LTD. (FI) 1987-09-29 US disclosed
EP-0095875-B1 NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE Farmos Group Ltd. (FI) 1986-09-10 EP disclosed
EP-0095875-A2 Novel tri-phenyl alkane and alkene derivatives and their preparation and use Farmos Group Ltd. (FI) 1983-12-07 EP disclosed
US-4228170-A INHIBITOR OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE SMITHKLINE CORPORATION (US) 1980-10-14 US disclosed