Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648961 | 0.86 | CARM1 (0.49) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL26648956 | 0.86 | CARM1 (0.49) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL8525336 | 0.85 | ALDH1A1 (0.51) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL9118362 | 0.85 | ALDH1A1 (0.51) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2022684 | 0.85 | ALDH1A1 (0.51) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL3731771 | 0.85 | TDP1 (0.50) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2023266 | 0.85 | ALDH1A1 (0.51) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2019099 | 0.83 | CARM1 (0.49) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2511239 | 0.83 | CARM1 (0.49) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL27872751 | 0.83 | CARM1 (0.49) | CARM1PRMT6CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960405-A | glutaminase inhibitors | 理森制药股份公司 | 2016-09-21 | — | — | CN | disclosed |