Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099147 | 0.89 | TSHR (0.41) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| Phosphonic Acid SCHEMBL27593948 | 0.83 | TSHR (0.48) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL7594351 | 0.80 | TAS1R3 (0.51) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL5170699 | 0.78 | TSHR (0.56) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL28647039 | 0.77 | CA12 (0.41) | TSHRTAS1R3TAS1R1CA12CA1 | |
| SCHEMBL12607570 | 0.76 | TSHR (0.39) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL25250018 | 0.75 | TSHR (0.52) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL2938364 | 0.73 | TSHR (0.50) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL21909974 | 0.73 | TSHR (0.50) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB | |
| SCHEMBL22080679 | 0.73 | TSHR (0.47) | TSHRTAS1R3TAS1R1SMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960420-A | Chain-end thiol-functionalized phosphorus-accumulating polymers and process for their preparation | 米其林集团总公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-105940028-A | Method for producing diene polymers bearing phosphorus functional groups, products resulting from said method and composition containing same | 米其林集团总公司 | 2016-09-14 | — | — | CN | disclosed |